MODAFINIL - AN OVERVIEW

Metabolism: Modafinil undergoes hepatic metabolism by means of multiple pathways, which includes CYP3A4. 80% from the dose is recovered within the urine in the form of metabolites.Ferraro et al (1996) in the first of a series of papers about modafinil’s steps showed using in vivo microdialysis in rats that modafinil decreases GABA within the medi